A Preparation and Quality Control of the [153Sm]-Samarium Maltolate Complex as a Lanthanide Mobilization Product in Rats
نویسندگان
چکیده
منابع مشابه
Preparation and Quality Control of the [153Sm]-Samarium Maltolate Complex as a Lanthanide Mobilization Product in Rats
Development of lanthanide detoxification agents and protocols is of great importance in management of overdoses. Due to safety of maltol as a detoxifying agent in metal overloads, it can be used as a lanthanide detoxifying agent. In order to demonstrate the biodistribution of final complex, [(153)Sm]-samarium maltolate was prepared using Sm-153 chloride (radiochemical purity >99.9%; ITLC and sp...
متن کاملPreparation and quality control of 153Sm-[tris(1,10 -phenanthroline) samarium (III)] complex
Background: The 153Sm-[tris(1,10-phenanthroline) Samarium(III)]complex (153Sm-PL3) was prepared in view of development of targeting therapeutic compounds for malignancies, and interesting in-vitro anti-tumor activities of lanthanide phenanthroline complexes,. Materials and Methods: Sm-153 chloride was obtained by thermal neutron flux (4 × 1013 n.cm-2.s-1) of enriched 152Sm2O3 sample, diss...
متن کاملthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
preparation and quality control of 153sm-[tris(1,10 -phenanthroline) samarium (iii)] complex
background: the 153sm-[tris(1,10-phenanthroline) samarium(iii)]complex (153sm-pl3) was prepared in view of development of targeting therapeutic compounds for malignancies, and interesting in-vitro anti-tumor activities of lanthanide phenanthroline complexes,. materials and methods: sm-153 chloride was obtained by thermal neutron flux (4 × 1013 n.cm-2.s-1) of enriched 152sm2o3 sample, dissolved ...
متن کاملDetermination of human absorbed dose from [153Sm]-Samarium maltolate based on distribution data in rats
Background: Therapeutic radiopharmaceuticals are designed to deliver high doses of radiation to selected target organs with an aim of minimizing unwanted radiation to surrounding healthy tissue. Due to the potential of targeted radiotherapy to treat a wide range of malignant conditions, [153Sm]-samarium maltolate was developed for possible therapeutic applications. Materials and Methods: The or...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2011
ISSN: 0036-8709,2218-0532
DOI: 10.3797/scipharm.1011-08